Consumption of Korean black RASPBERRY proved beneficial in reducing the risk of cardiovascular disease - El consumo de FRAMBUESA negra coreana resultó beneficioso para reducir el riesgo de enfermedades cardiovasculares

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Overconsumption of fructose results in dyslipidemia, hypertension, which have documented as a risk of cardiovascular diseases. A experimental study was designed to investigate the beneficial effects of the "Korean black raspberry" Rubus coreanus Miq .(RCM) in high-fructose diet-induced metabolic syndrome. Mices were divided into three groups: (1) control group fed regular diet and tap water, fructose groups were fed the 65% high-fructose (HF) diet with (2)/without (3) RCM 100 mg/kg/day for 8 weeks, respectively. Chronic treatment with RCM significantly decreased body weight, fat weight and adipocyte size. Moreover, RCM significantly prevented the development of the metabolic disturbances such as hyperlipidemia and hypertension. RCM also led to increase in high density lipoprotein level in the HF group. In addition, RCM suppressed vascular cell adhesion molecule-1 (VCAM-1) expression and significantly recovered the levels of endothelial nitric oxide synthase (eNOS) expression in aorta. These results demonstrates that RCM may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, and hypertension.

Source: Korean Journal of Oriental Physiology and Pathology. 2015. Apr, 29(1): 11-17.